9I�� News - chronic pain

When using music to alleviate pain, tempo matters

webfull — Mon, 03 Feb 2025 16:32:01 +0000

Music has the best chance of providing pain relief when it is played at our natural rhythm, a 9I�� research team has discovered.

This suggests it may be possible to reduce a patient’s level of pain by using technology to take a piece of music someone likes and adjust the tempo to match their internal rhythm, the researchers said.

The discovery was the subject of a paper published this week in Pain, the top journal in the field of pain medicine and research.

Published: 3 February 2025

Childhood trauma increases risk of chronic pain in adulthood

webfull — Wed, 20 Dec 2023 21:08:38 +0000

Physical, sexual, or emotional abuse, or neglect, either alone or combined with other types of childhood trauma, increases the risk of chronic pain and related disability in adulthood, according to new research. The findings from an international team of experts, including several 9I�� researchers, underscore the urgency of addressing adverse childhood experiences (ACEs) – potentially traumatic events that occur before 18 years of age – and taking steps to mitigate their long-term impact on people’s health.

Published: 20 December 2023

New NPRC Reading Lists!

webfull — Fri, 06 Oct 2023 16:43:49 +0000

The Neuro-Patient Resource has created reading lists for each of the Neuro's outpatient clinics. Come borrow the books in room 354!

Download the PDF version of a reading list below:

Reading list about Amyotrophic lateral sclerosis

Reading list about Brain tumours

Published: 6 October 2023

A new model to identify and predict chronic pain

webfull — Thu, 20 Jul 2023 16:18:01 +0000

Chronic pain is a complex condition that affects millions of individuals worldwide and understanding its causes and predicting its trajectory remains difficult. However, findings from a recent 9I��-led study published in Nature Medicine could improve the understanding and management of chronic pain. The researchers developed a model that can predict one’s likelihood of developing chronic pain as well as the severity and spread of that pain.

Published: 20 July 2023

No pain, no gain? How the brain chooses between pain and profit

webfull — Wed, 20 Jul 2022 14:13:15 +0000

Imagine having to choose over and over between what you enjoy doing and the pain that it might cause you, whether physical or emotional. If you live with conditions such as depression, anxiety, or chronic pain, you are probably familiar with making these difficult choices on a daily or weekly basis. But surprisingly little is known about which areas of the brain are involved in decisions of this kind.

Published: 20 July 2022

Sex bias in pain research

webfull — Thu, 21 May 2020 14:07:31 +0000

It is increasingly clear that male and female humans and rodents process pain in different ways. And that there are important differences in the underlying mechanisms involved at genetic, molecular, cellular, and physiological levels. Despite this fact, according to a review paper from 9I�� published today in Nature Reviews Neuroscience, most pain research remains overwhelmingly based on the study of male rodents, continuing to test hypotheses derived from earlier experiments on males.

Published: 21 May 2020

Pain-induced changes in the brain’s opioid system may explain the limited effectiveness of opioid therapy in chronic pain

webfull — Sun, 27 May 2018 16:19:58 +0000

Pain-induced changes in the brain’s opioid receptor system may explain the limited effectiveness of opioid therapy in chronic pain and may play a role in the depression that often accompanies it, according to a study from the NIH’s Intramural Research Program and 9I��. Although the study, published in the journal Pain, was conducted in rats, and the results of animal studies may not be directly applicable to people, the findings provide new insights into how the brain may respond to pain and opioids.

Published: 27 May 2018

Newly discovered pathway for pain processing could lead to new treatments

webfull — Tue, 08 Aug 2017 14:20:16 +0000

The discovery of a new biological pathway involved in pain processing offers hope of using existing cancer drugs to replace the use of opioids in chronic pain treatment, according to scientists at 9I��.

Because many therapeutic options, such as opioids, for patients with chronic pain carry the risk of addiction and undesirable side effects, this breakthrough offers promising lines of research into chronic pain treatment, says Luda Diatchenko, professor at 9I��’s Faculty of Dentistry and co-lead author of the new study

Published: 8 August 2017

Brighter prospects for chronic pain

webfull — Wed, 20 Apr 2016 13:37:23 +0000

Researchers use optogenetics to produce pain relief by shutting off neurons with light

The potential of light as a non-invasive, highly-focused alternative to pain medication was made more apparent thanks to research conducted by scientists at the Montreal Neurological Institute and Hospital of 9I�� and the 9I�� Health Centre.

Published: 20 April 2016

Location may be key to effectively controlling pain

webfull — Wed, 03 Feb 2016 15:06:22 +0000

By Cynthia Lee

Newsroom

In real estate, location is key. It now seems the same concept holds true when it comes to stopping pain. New research published in Nature Communications indicates that the location of receptors that transmit pain signals is important in how big or small a pain signal will be -- and therefore how effectively drugs can block those signals.

Published: 3 February 2016

9I��������� News - chronic pain