Large international study will help select and categorize patients for better clinical trials
A large multi-centre study of more than 1,200 patients provides important predictors of Parkinson鈥檚 disease progression, which will allow better candidate selection for clinical trials and more effective therapy development.
Scientists prove difference between expected/actual outcomes cause reward response
If you love it when a musician strikes that unexpected but perfect chord, you are not alone. New research shows the musically unexpected activates the reward centre of our brains, and makes us learn about the music as we listen.
Researchers seek to answer longstanding debate
Scanner will deliver clear images of the nervous system in exceptional detail
Scientists will see the human nervous system in microscopic detail thanks to the installation of Canada鈥檚 first 7-Tesla whole-body magnetic resonance imaging (MRI) scanner on Feb. 5.
Technique involves use of non-invasive digital infrared imaging
Reinhardt lab receives 5-year CIHR grant to investigate extracellular matrix-mediated regulation of microRNAs in health and disease. Congratulations!
9I制作厂免费 and MUHC research teams part of an international effort to uncover how chronic inflammation causes cancer
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Ghrelin promotes conditioning to food-related odours
The holiday season is a hard one for anyone watching their weight. The sights and smells of food are hard to resist. One factor in this hunger response is a hormone found in the stomach that makes us more vulnerable to tasty food smells, encouraging overeating and obesity. New research on the hormone ghrelin was published on Dec. 4, 2018, led by Dr. Alain Dagher鈥檚 lab at the Montreal Neurological Institute and Hospital of 9I制作厂免费.
Reducing stigma may address cognitive impairment in this population
A new study has drawn a direct link between the amount of stigma men with HIV report experiencing and their scores on cognitive tests, measuring abilities such as memory and attention.
Concerns raised about efficacy of off-label use of already approved drugs
A new paper published by 9I制作厂免费 researchers in JAMA Internal Medicine suggests that some clinical trials may promote the use of ineffective and costly treatments. That鈥檚 the opposite of what clinical trials are aimed at, namely preventing ineffective and costly treatments from being taken up by physicians and patients.
Source: MUHC Newsroom
Source: Cell Metabolism
New research suggests that higher-level brain functions have a major role in losing weight. In a study among 24 participants at a weight-loss clinic, those who achieved greatest success in terms of weight loss demonstrated more activity in the brain regions of the lateral prefrontal cortex associated with self-control. The results of the study were published in听Cell Metabolism听on October 18.
Brain cancer begins in stem cells, targeting them may prevent tumour growth
Researchers at the Montreal Neurological Institute and Hospital (The Neuro) have found an exciting new way of treating brain cancer.
Late stage brain cancer cells are heterogeneous 鈥� they differ down to the molecular level. This makes developing treatments at this stage difficult, because a drug that may be effective against one cell may not be effective against another.
Researchers discover additional targets for existing drugs used to treat a specific melanoma
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A set of targeted cancer drugs, known as BRAF and MEK inhibitors, have proven to be beneficial for some metastatic melanoma patients whose tumours include a specific mutation in the BRAF gene, known as V600E. A recent study conducted in the lab of Dr. Peter Siegel at 9I制作厂免费鈥檚 Goodman Cancer Research Centre suggests that these same drugs may prove beneficial for a broader range of cancer patients.
