/tropmed/fr/aggregator Centre J.D. MacLean pour maladies tropicales - flux agrégés fr https://pubmed.ncbi.nlm.nih.gov/40610361/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20250704002539&v=2.18.0.post9+e462414 BACKGROUND: Presymptomatic or asymptomatic immune system signals and subclinical physiological changes might provide a more objective measure of early viral upper respiratory tract infections (VRTIs) compared with symptom-based detection. We aimed to use multimodal wearable sensors, host-response biomarkers, and machine learning to predict systemic inflammation following controlled exposure to a live attenuated influenza vaccine, without relying on symptoms. Thu, 03 Jul 2025 06:00:00 -0400 https://pubmed.ncbi.nlm.nih.gov/40596793/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20250703013050&v=2.18.0.post9+e462414 Cases of infection with the canine hookworm Ancylostoma caninum that are resistant to all anthelmintic classes registered in the United States of America (USA) for control of this parasite in dogs were first reported in 2019. Termed Multiple Anthelmintic Drug Resistance (MADR), cases have subsequently been reported in pet dogs across the USA. Recent studies using molecular tests that detect mutations known to cause resistance to benzimidazole anthelmintics have revealed an alarming frequency of... Wed, 02 Jul 2025 06:00:00 -0400 https://pubmed.ncbi.nlm.nih.gov/40591727/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20250702030354&v=2.18.0.post9+e462414 The monitoring and evaluation (M&E) framework for the World Health Organization (WHO) Neglected Tropical Diseases (NTD) road map includes both quantitative and qualitative assessments of progress at key timepoints up to 2030. These assessments provide critical information to improve programmatic action and identify immediate research needs. Quantitative assessments process multi-sourced data on a predefined number of global indicators. Qualitative assessments are based on results obtained from... Tue, 01 Jul 2025 06:00:00 -0400 https://pubmed.ncbi.nlm.nih.gov/40577550/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20250628031447&v=2.18.0.post9+e462414 In the wake of a large outbreak in Reunion and Mayotte the GeoSentinel network has been signalling chikungunya cases among returning travellers acquired in multiple African and Asian countries between August 1st 2024 and June 10th 2025. These surveillance data suggest a resurgence of chikungunya in the Indian Ocean Region. Fri, 27 Jun 2025 06:00:00 -0400 https://pubmed.ncbi.nlm.nih.gov/40556808/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20250626004606&v=2.18.0.post9+e462414 CONCLUSION: CPG-supported mAb administration for management of COVID-19 in high-risk patients was associated with favourable clinical outcomes and may be a useful model to guide future therapies. Wed, 25 Jun 2025 06:00:00 -0400 https://pubmed.ncbi.nlm.nih.gov/40526084/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20250618011924&v=2.18.0.post9+e462414 Antimicrobial combinations have been extensively evaluated in vitro to identify synergistic combinations for clinical use. Despite the available literature, no studies comprehensively summarize the findings for antimicrobial combinations against Staphylococcus aureus. We performed a systematic review to identify synergistic combinations that may be beneficial for clinical use against S. aureus. The PubMed, Cochrane, and Web of Science databases were queried from inception to February 2024 for... Tue, 17 Jun 2025 06:00:00 -0400 https://pubmed.ncbi.nlm.nih.gov/40440719/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20250530002848&v=2.18.0.post9+e462414 No abstract Thu, 29 May 2025 06:00:00 -0400 https://pubmed.ncbi.nlm.nih.gov/40401576/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20250523024349&v=2.18.0.post9+e462414 Over 70% of organic halogens, representing chlorine- and bromine-containing disinfection byproducts (Cl-/Br-DBPs), remain unidentified after 50 years of research. This work introduces a streamlined and cloud-based exposomics workflow that integrates high-resolution mass spectrometry (HRMS) analysis, multistage machine learning, and cloud computing for efficient analysis and characterization of Cl-/Br-DBPs. In particular, the multistage machine learning structure employs progressively different... Thu, 22 May 2025 06:00:00 -0400 https://pubmed.ncbi.nlm.nih.gov/40383028/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20250519011758&v=2.18.0.post9+e462414 Every second, a person with diabetes develops a foot ulcer. At least half of these wounds become infected, which dramatically increases the risk of hospitalization, amputation, and death. Wound environment pH is a possible marker of infection, however, clinical application has yet to be achieved. Herein, we introduce a hydrogel sheet dressing made out of a transparent calcium alginate body, which is embedded by a pH-sensitive color changing dye named α-naphtholphthalein that equilibrates to... Sun, 18 May 2025 06:00:00 -0400 https://pubmed.ncbi.nlm.nih.gov/40339791/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1zSVwQViw4htk0ptJE-rdb4g98Hn0Vy51ceCnixBnFkL6ILsbf&fc=20201106102241&ff=20250510002110&v=2.18.0.post9+e462414 CONCLUSIONS: Direct and indirect evidence of C. burnetii or Bartonella sp. infections was observed in persistent fever cases. Further studies are necessary to elucidate the burden of these diseases in LMICs. Thu, 08 May 2025 06:00:00 -0400