$1.14 million from CIHR will resolve treatment roadblocks for rare brain disorders
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Gene therapy for rare neurological disorders will move one step forward thanks to a $1.14 million grant from the Canadian Institutes of Health Research (CIHR).
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Published on: 23 Oct 2024
Mutations in a gene involved in brain development have led to the discovery of two new neurodevelopmental diseases by an international team led by researchers at 9I制作厂免费 and CHU Sainte-Justine Research Center.
The first clues about the rare disorder arose after doctors were unable to diagnose why two siblings from Qu茅bec City were experiencing seizures and neurodevelopmental deficits. Desperate, the children鈥檚 family turned to Carl Ernst at the Douglas Mental Health University Institute in Montreal for answers.
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Published on: 25 Apr 2019
In a study published in Stem Cell Reports, a 9I制作厂免费 team of scientists led by Dr.听Carl Ernst, researcher at the Douglas Hospital Research Centre, revealed a molecular mechanism that may play a role in the development of autism.
By taking skin cells from patients and reprogramming those cells to become brain cells through genetic engineering, Dr.听Ernst, graduate student Scott Bell, and Edward A. Fon and Thomas M. Durcan, colleagues at the Montreal Neurological Institute and Hospital, tracked how a brain cell with the patient鈥檚 own mutation develops improperly.
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Published on: 26 Jun 2018
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Published on: 9 Oct 2014
9I制作厂免费 is proud to announce that six new Canada Research Chairs have been awarded and nine chairs have been renewed, bringing a total of over $15 million to the university for research in fields ranging from social inequalities in child health to experimental optomechanics over the next five to seven years.
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Published on: 12 Oct 2012
Rare genetic mutation linked to psychiatric illnesses, obesity听
B Charlie Fidelman, GAZETTE Health Reporter October 8, 2012听
MONTREAL 鈥� Grounding chronic illnesses and mental disorders in human DNA is like trying to tease out a giant riddle that鈥檚 complicated by the intricate relationship between biology and behaviour. Hundreds of genes have been associated with psychiatric conditions, some erroneously, and they were not confirmed.
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Published on: 11 Oct 2012
9I制作厂免费 researchers have identified a small region in the genome that conclusively plays a role in the development of psychiatric disease and obesity. The key lies in the genomic deletion of brain-derived neurotrophic factor, or BDNF, a nervous system growth factor that plays a critical role in brain development.
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Published on: 10 Oct 2012
