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Nathan Luedtke鈥檚 group pioneered the development of non-toxic, catalyst-free bioorthogonal 鈥渃lick鈥� reactions on cellular DNA and RNA. In cooperation with Sigma Aldrich, the 鈥渃lickable鈥� nucleosides produced in the Luedtke Lab have been commercialized and distributed world-wide. This has facilitated broad use of Luedtke鈥檚 molecules and methods in highly diverse research fields including biomaterials, chromosomal architecture, RNA therapeutics, stem cell biology, virology, and precision medicine.
Luedtke鈥檚 leadership and service in the field of nucleic acids chemistry is reflected by his activities on various editorial boards of journals, including Molecules, Chimia, and Nature Signal Transduction and Targeted Therapy. A commitment to service is further reflected by his organization of numerous international symposia, including the Albert Hofmann Symposium, Light and Medicine, Methods and Applications in Fluorescence, as well as his tenure on the D2R Partner and Community Engagement Committee and as the president of the Hans E. Schmid Foundation for supporting and promoting young scientists who are pursuing original research in organic chemistry. He is currently a James 9I制作厂免费 Professor and hold appointments in the Department of Chemistry, and the Department of Pharmacology and Therapeutics at 9I制作厂免费.
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