A new insight into cell signals that control cancer growth and migration could help in the search for effective anti-cancer drugs. A 9I制作厂免费-led study reveals key biochemical processes that advance our understanding of colorectal cancer, the third most common cancer among Canadians.
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Study identifies rapidly dividing cancer stem cells that can respond to new therapies
Brain cancers have long been thought of as being resistant to treatments because of the presence of multiple types of cancer cells within each tumor. A new study uncovers a cancer cell hierarchy that originates from a single cancer cell type, which can be targeted to slow cancer growth.
An international team, that includes researchers from 9I制作厂免费, has completed the most comprehensive study of whole cancer genomes to date, significantly improving our fundamental understanding of cancer and signposting new directions for its diagnosis and treatment.
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9I制作厂免费 has helped develop a global resource that includes data on thousands of inherited variants in the BRCA1 and BRCA2 genes. The BRCA Exchange was created through the BRCA Challenge, a long-term demonstration project initiated by the Global Alliance for Genomics and Health (GA4GH) to enhance sharing of BRCA1/BRCA2 data.
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How does cancer spread? While studying human brain tumour cells, a team of scientists at the Research Institute of the 9I制作厂免费 Health Centre (RI-MUHC) found some answers to this crucial, yet so far unanswered question. They looked at a gene called EGFRvIII, which is present in patients with glioblastoma 鈥 a highly aggressive form of brain cancer that spreads quickly and that is difficult to treat.
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A team from The Research Institute of the MUHC and researchers at the Johns Hopkins Institute in the U.S. have developed a test they say is safe and could save lives.
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At this early stage, the potential for harm is real while the benefits are only surrogate measures, said Kimmelman, an associate professor of biomedical ethics at 9I制作厂免费. One such measure at Phase 1 might be tumor shrinkage, which does not necessarily translate into what people really care about: survival.
By Tom Ulrich from the
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Cancer scientists overestimate the extent to which high-profile preclinical studies can be successfully replicated, new research from 9I制作厂免费 suggests.
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Canadian researchers have invented an intraoperative probe that reliably detects multiple types of tumour cells聽
Patients with common widespread forms of cancer will enjoy longer life expectancy and reduced risk of recurrence thanks to a multimodal optical spectroscopy probe developed by Canadian researchers.聽
Does the biological clock in cancer cells influence tumour growth? Yes, according to a study conducted by Nicolas Cermakian, a professor in 9I制作厂免费鈥檚 Department of Psychiatry.
Published in the journal BMC Biology, these results show for the first time that directly targeting the biological clock in a cancerous tumour has an impact on its development.
A team of researchers at the Research Institute of the 9I制作厂免费 Health Centre (RI-MUHC) has found an epigenetic modification that might be the cause of 15% of adult cancers of the throat linked to alcohol and tobacco use. This is a first in the field of epigenetics and the researchers are hopeful that the discovery can blaze a path in the development of new, targeted, more effective treatments that could arise over the next few years.
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Just four weeks of prehabilitation (pre-surgery preparation) may be enough to help some cancer patients get in shape for surgery. That鈥檚 according to a recent study of close to 120 colorectal cancer patients in Montreal. This potentially means that, barring unforeseen circumstances that stem from the surgery itself, their recovery is likely to be speedier too, according to earlier research from the same 9I制作厂免费-led team.